Kidney / Renal Transplant in India

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What is a Kidney?

The kidneys, positioned in the upper abdomen, are digestive organs with a pear-shaped structure. They play a crucial role in various bodily functions, primarily serving to filter blood and eliminate waste products, thus maintaining a balance in the body's electrolyte levels.

Additionally, the kidneys play a vital role in regulating blood pressure and promoting the generation of red blood cells. Positioned on either side of the spine in the abdomen, each kidney receives blood directly from the aorta through the renal arteries and returns it to the heart through the renal veins connected to the vena cava.

The transplantation procedure involves a surgical process in which the new kidney is positioned in the abdomen. The surgeon connects it to the artery that previously supplied blood to one of your kidneys and to the vein responsible for carrying blood away from the kidney. Additionally, the ureter, responsible for transporting urine from the kidney to the bladder, is attached to the newly transplanted kidney.

What is a Kidney Transplant?

Substituting malfunctioning or diseased kidneys with a healthy kidney obtained from either a living or brain-dead donor is the essence of kidney transplantation. It's noteworthy that individuals can lead a healthy and extended life with just one properly functioning kidney. This procedure is typically recommended for patients grappling with end-stage renal disease. Kidney transplant surgeries come in two primary types:

Living Donor Kidney Transplant Surgery : The kidney is sourced from a close family member or a compatible and willing spouse. However, before a candidate is accepted, a comprehensive examination of the potential donor is conducted to ensure suitability.

Cadaveric or Deceased Donor Kidney Transplant Surgery : In this scenario, the kidney is procured from a person who is brain-dead, and their family members have given consent for organ donation. Rigorous blood tests are conducted on both the donor and the recipient as part of the thorough evaluation process.

For a more in-depth understanding of the criteria for kidney transplantation, it is recommended to refer to the Kidney/Renal Transplant Guidelines in India. These guidelines offer comprehensive information on the specific criteria and prerequisites for kidney transplant procedures within the country.

Types of Kidney Diseases

The condition characterized by a reduction in kidney function is referred to as 'kidney disease.' There are two main types of kidney diseases: acute kidney disease, marked by sudden damage with rapid symptom manifestation, and chronic kidney disease, characterized by a gradual and progressive decline in kidney function over time. Various types of kidney diseases include:

  • Kidney Cancer
  • Early Kidney Failure
  • Chronic Renal Insufficiency
  • Nephropathy
  • Hyperfiltration (Stage 1)
  • Mild Microalbuminuria ( Stage 2 )
  • Clinical Albuminuria ( Stage 3)
  • Advanced Clinical Nephropathy (Stage 4)
  • Kidney Failure (Stage 5)
  • Diabetic Nephropathy
  • Nephritis

Causes of Kidney Diseases

  • Diabetes mellitus, a condition that impairs small blood vessels throughout the body, posing challenges to proper kidney function.
  • Untreated high blood pressure, or hypertension, can lead to damage to the glomeruli, the structures responsible for filtering waste from the body.
  • Glomerulonephritis results in the leakage of red blood cells from the kidneys into the urine.
  • Polycystic Kidney Disease is characterized by the development of clusters of fluid-filled cysts in the kidneys.
  • Renovascular disease is a condition that leads to reduced blood flow to the kidneys.
  • Chronic pyelonephritis is brought about by recurrent episodes of urinary tract infections.
  • Systemic Lupus Erythematosus is a condition where the body mistakenly attacks its own kidney tissues.
  • Obstructive Nephropathy refers to the blockage of urine flow, leading to damage in the kidneys.
  • Analgesic Nephropathy occurs when the kidneys are damaged due to the overuse of analgesic drugs and medications in excessive quantities.

Types of Kidney Treatments

Acute Kidney Diseases Treatment : The approach to treatment hinges on both the causes and the extent of kidney failure. The primary objectives include identifying the precise cause of kidney failure and assessing the impact of accumulating wastes and water on the body. The treatment plan is then determined based on these considerations.

Chronic Kidney Diseases Treatment : The primary objective is to prevent or decelerate further damage to the kidneys. A crucial aspect is to manage and control the underlying disease responsible for kidney damage. In the case of a diabetic patient, the doctor will strategize a comprehensive approach to treat and manage diabetes, aiming to slow down additional kidney damage. Additionally, the healthcare provider will investigate other potential factors contributing to kidney damage, such as urinary tract blockages or medication overdoses.

Procedure of Kidney transplant

The procedure commences with the placement of the new kidney on the lower right or left side of the patient's abdomen, where nearby blood vessels are surgically connected. Specifically, the artery and vein of the kidney are attached just above one of the legs to an artery and vein in the lower part of the abdomen. To facilitate the passage of urine out of the patient's body, the ureter of the new kidney, the tube linking the kidney to the bladder, is connected to blood vessels and the bladder.

Benefits of Kidney Transplant

A successful kidney transplant can bring about significant improvements in the patient's life. Post-surgery, the patient can resume a normal lifestyle, including a regular diet and increased fluid intake. Not having to rely on dialysis is a notable advantage. Additionally, issues like anemia, common in kidney failure, may be rectified. The success rate is contingent upon factors such as the type and number of organs transplanted, as well as the underlying disease causing organ failure. Single organ transplants typically exhibit a success rate ranging from 80% to 90%, with a 5-10 year survival rate.

Post-operative Care of the Kidney Transplant

Post-operative care entails the daily intake of medications to prevent the immune system from rejecting the newly transplanted organ. The quantity of medicines may vary over time, with a higher requirement for anti-rejection medications immediately after the transplant. Adopting healthy habits is crucial, including a nutritious diet, regular exercise, ensuring good sleep, and avoiding exposure to large crowds. These precautions contribute to the overall well-being of the transplant recipient.

Cost of Kidney Transplant

In contrast to international healthcare expenses, the cost of a kidney transplant in India, which often includes dialysis, is notably reasonable. Indian hospitals cater to around 5,000 kidney patients every year, drawing individuals from across the globe. Despite the global reach and high-quality medical care offered, the costs in India remain comparatively low, making it an attractive destination for those seeking affordable and effective kidney treatment.

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